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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGDIA All Species: 24.24
Human Site: Y27 Identified Species: 48.48
UniProt: P52565 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52565 NP_004300.1 204 23207 Y27 E D E H S V N Y K P P A Q K S
Chimpanzee Pan troglodytes XP_001164704 183 21106
Rhesus Macaque Macaca mulatta XP_001112043 178 20308
Dog Lupus familis XP_849933 204 23375 Y27 E D E H S V N Y K P P A Q K S
Cat Felis silvestris
Mouse Mus musculus Q99PT1 204 23389 Y27 E D E H S V N Y K P P A Q K S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515491 219 25235 Y42 G D E V E L A Y Q A P E K K S
Chicken Gallus gallus NP_001074340 204 23256 Y27 E D E H S V N Y K P P A R K S
Frog Xenopus laevis NP_001085674 204 23448 Y27 D E E H S V D Y K P P A Q K S
Zebra Danio Brachydanio rerio NP_998626 203 23057 Y26 E Q G E S V N Y K A P A Q K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20496 191 21900 Q15 G E N T S E Y Q Y K Q P P Q K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFC6 240 27213 L62 E E D D D S K L Q L G P Q Y T
Baker's Yeast Sacchar. cerevisiae Q12434 202 23120 K25 D Q Y K V S A K K T V D E Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.7 87.2 97.5 N.A. 97 N.A. N.A. 62 91.1 78.4 81.3 N.A. N.A. N.A. 37.7 N.A.
Protein Similarity: 100 89.7 87.2 99.5 N.A. 99.5 N.A. N.A. 76.2 97.5 88.2 91.1 N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: 100 0 0 100 N.A. 100 N.A. N.A. 40 93.3 80 73.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 0 0 100 N.A. 100 N.A. N.A. 60 100 100 73.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 33.3 39.7 N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 61.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 17 0 0 17 0 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 42 9 9 9 0 9 0 0 0 0 9 0 0 0 % D
% Glu: 50 25 50 9 9 9 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 9 9 59 9 0 0 9 59 17 % K
% Leu: 0 0 0 0 0 9 0 9 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 42 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 42 59 17 9 0 0 % P
% Gln: 0 17 0 0 0 0 0 9 17 0 9 0 50 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 59 17 0 0 0 0 0 0 0 0 59 % S
% Thr: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 9 % T
% Val: 0 0 0 9 9 50 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 9 59 9 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _